Innovative Solution
Why Choose Advancexo?
- Powered by the regenerative intelligence of billions of exosomes sourced from the most potent stem cells.
- Scientifically validated and approved by dermatologists for safety and efficacy.
- Ensured Prolonged Stability and Shelf Life at Room Temperature for lasting efficacy.
- Exclusively manufactured in India by the Advancells Group, renowned for its decades-long leadership in regenerative science.
“Experience Cell-Free Regeneration to Revel in Skin and Hair as Silky and Supple as a Newborn’s,,
Transforming Skin & Hair Health with Innovative Technology
Advancexo Skin Rejuve Kit for a Transformative Change in the Skin
- Dark Spots: Enhances skin clarity and reduces hyperpigmentation from photoaging and sun damage.
- Dull Skin: Maintains hydration, smoothness, and glow by preventing epidermal water loss.
- Wrinkles and Fine Lines: Noticeable reduction in fine lines and wrinkles, resulting in a youthful complexion.
- Loss of Firmness: Boost collagen and elastin production to achieve firmer, tighter skin.
- Self-Regeneration: Promotes self-regenerative ability of the skin to combat melasma, acne, tanning, and inflammation.
- Turnover: Activates skin renewal pathways for brightening, soothing, and recovery.
Advancexo Hair Rejuve Kit for a Transformative Change in the Hair
- Synergistic Benefits: Dual action on both scalp and hair at the same time.
- All-in-One Solution: Effectively addresses various hair concerns like Alopecia, Hair Thinning, Hair loss, etc.
- Hair Loss: Significantly boosts hair counts and volume for both men and women.
- Genetic Hair Concerns: Activated with key ingredients to tackle genetic issues for hair loss, hair thinning, and low hair density.
Preparation for Treatment
Step 1: With the help of a syringe, draw bio activating solution from Rejuve kit vial B.
Step 2: Transfer the drawn bioactivating solution to Rejuve kit vial A containing lyophilized exosomes.
Step 3: Gently shake the reconstituted exosomes for 30 seconds to mix the components thoroughly.
Step 4: Apply reconstituted Advancexo on the target area as per your protocol.
Testimonials
Before
• Dark spots
• Uneven skin texture
• Oily skin
• Hyperpigmentation
After
• Reduction in dark spots after 7 days
• Oil control and reduction in pore was observed
• No active acne was observed
• Skin brightening and even skin tone with in 1 month
Faizan, an actor, recently underwent skin treatment under the guidance of Dr. Amit Bhasin. Following his initial treatment, his dermatologist opted for Advancexo to minimize potential post-treatment side effects and promote optimal healing.
Dr. Vishal Rampuri, a leading dermatologist, is utilizing Advancexo, a novel therapeutic approach, for the treatment of a patchy scalp in a male patient. Advancexo's unique combination of lyophilized exosomes and growth factors help address hair loss.
Before
• Tanning on forehead
• Oily T-Zone
• Uneven skin tone
• Open pores
After
• Tanning reduced in 1 week
• Oil control observed within 3 days of application
• Smooth skin texture
• Reduced open pores
Before
• Scanty Baldness
• Hair follicle weakening
• Hair thinning
• Hair fall
After
• Hair follicle regeneration
• Reduction in baldness
• Improved hair density
• Scalp rejuvenation
Before
• Hair thinning at the top of the head
• Baldness in the crown of head
• Hair fall
• Hair follicle weakening
• Flaky scalp
After
• Reduction in Baldness at the crown of head
• Reduces hair fall
• Improve hair density at the top of the head
• Hydrated scalp
• Hair follicle regeneration
Before
• Scarring alopecia at the crown of head
• Hair fall
• Flaky scalp
• Patchy bald spots
After
• Reduced bald spot at the crown of head
• Improved hair density
• Hydrated scalp
• Stop of hair fall
Before
• Alopecia at the crown of the head
• Hair follicle weakening
• Hair thinning
• Brittle hair
After
• Hair follicle rejuvenation
• Restoration of hair at the crown of the head
• Improved hair density
• Stronger hair strand
Before
• Melasma
• Uneven skin tone
• Grey brown patches
After
• Reduction in pigmentation
• Improved skin tone
• Restoring natural skin tone and complexion
Before
• Alopecia
• Hair loss path at head crown
• Hair thining
• Dry scalp
Brittle hair
After
• Hair restoration
• Reduced hair loss patch
• Improved hair density
• Hydrated scalp
• Increased hair thickness
Before
• Uneven skin texture
• Uneven skin tone
• Deep Nasolabial folds
• Fine lines
After
• Improved skin texture
• Even skin tone
• Reduction in Nasolabial folds
• Reduction in fine lines
Before
• Acne scars
• Darkspots
• Nasolabial folds
After
• Reduced acne scars
• Even skin tone
• Reduction in Nasolabial folds
Before
• Alopecia
• Hair loss patch at the head crown
• Hair follicle weakening
• Hair thinning in crown region
After
• Hair restoration
• Hair loss at head crown
• Stimulate hair follicle
• Increased hair density and thickness
Before
• Dark spots
• Uneven skin texture
• Oily skin
• Hyperpigmentation
After
• Reduction in dark spots after 7 days
• Oil control and reduction in pore was observed
• No active acne was observed
• Skin brightening and even skin tone with in 1 month
Faizan, an actor, recently underwent skin treatment under the guidance of Dr. Amit Bhasin. Following his initial treatment, his dermatologist opted for Advancexo to minimize potential post-treatment side effects and promote optimal healing.
Dr. Vishal Rampuri, a leading dermatologist, is utilizing Advancexo, a novel therapeutic approach, for the treatment of a patchy scalp in a male patient. Advancexo's unique combination of lyophilized exosomes and growth factors help address hair loss.
Before
• Tanning on forehead
• Oily T-Zone
• Uneven skin tone
• Open pores
After
• Tanning reduced in 1 week
• Oil control observed within 3 days of application
• Smooth skin texture
• Reduced open pores
Before
• Scanty Baldness
• Hair follicle weakening
• Hair thinning
• Hair fall
After
• Hair follicle regeneration
• Reduction in baldness
• Improved hair density
• Scalp rejuvenation
Before
• Hair thinning at the top of the head
• Baldness in the crown of head
• Hair fall
• Hair follicle weakening
• Flaky scalp
After
• Reduction in Baldness at the crown of head
• Reduces hair fall
• Improve hair density at the top of the head
• Hydrated scalp
• Hair follicle regeneration
Before
• Melasma
• Uneven skin tone
• Grey brown patches
After
• Reduction in pigmentation
• Improved skin tone
• Restoring natural skin tone and complexion
Before
• Alopecia
• Hair loss path at head crown
• Hair thining
• Dry scalp
Brittle hair
After
• Hair restoration
• Reduced hair loss patch
• Improved hair density
• Hydrated scalp
• Increased hair thickness
Before
• Uneven skin texture
• Uneven skin tone
• Deep Nasolabial folds
• Fine lines
After
• Improved skin texture
• Even skin tone
• Reduction in Nasolabial folds
• Reduction in fine lines
Before
• Acne scars
• Darkspots
• Nasolabial folds
After
• Reduced acne scars
• Even skin tone
• Reduction in Nasolabial folds
Before
• Alopecia
• Hair loss patch at the head crown
• Hair follicle weakening
• Hair thinning in crown region
After
• Hair restoration
• Hair loss at head crown
• Stimulate hair follicle
• Increased hair density and thickness
Nano Wonder with Mega Benefits Packed in a Vial!
- Brighter and even skin tone within 1 month
- Oil control with reduction in pores and active acne
- Reduction in dark spots and pigmentation
- Active acne management
- Remove fine lines and wrinkles
- Hydrate skin and makes it more elastic
- Boosts Collagen Synthesis in Scalp
- Stimulates hair follicles and initiates hair restoration
- Promotes healthier hair growth with improved density and texture
- Regenerate hair follicles
- Reduce Hair fall
Our Ingredients
Advancexo delivers a powerful complex of naturally occurring growth factors, proteins, and anti-inflammatory cytokines packed within billions of exosomes. Along with several growth factors, our team has identified and incorporated 56 specifically chosen miRNAs and 165 unique peptides and proteins, validated by Liquid Chromatography Mass Spectroscopy (LCMS). All working together to promote healthier, younger-looking skin and thick, luscious hair. A few of them are listed herewith:
Growth Factors | Functions |
Fibronectin | Helps maintain skin elasticity, and prevent aging. It is also useful in normal wound healing(1) |
Actin Cytoplasmic 1 | Prevents formation of reactive oxygen species (ROS), responsible for aging(2) |
Keratin, type II cytoskeletal | For hair growth, and skin regeneration(3),(4) |
Keratin, type II cytoskeletal 2 epidermal | Associated with keratinocyte activation, proliferation, and skin keratinization(5) |
Plasminogen activator inhibitor 1 | Promotes vascularization in skin(6) |
Albumin | For skin firmness and gloss(7) |
Actin | For promoting vascularization and improving blood supply(8) |
Inter-alpha-trypsin inhibitor | Prevents inflammation and aging(9) |
Complement C3 | Prevents scarring alopecia such as lupus erythematosus(10) |
Gelsolin | Helps in faster epidermal wound healing(11) |
Pentraxin-related protein PTX3 | Prevents inflammation, a major defender against infectious disorders(12) |
Alpha-2-macroglubulin | Helps reduce inflammation, effective against alopecia.(13) |
Thrombospondin-1 | Healing skin wounds(14) |
Vinculin | Promotes proliferation of hair follicle stem cells and epithelial stem cells(15) |
Collagen alpha1(VI) chain | Build hair proteins and strengthen skin(16) |
Periostin | Promotes wound healing and reduces fibrotic scar(17) |
Pigment epithelial-derived factor | Produced during wound healing, prevents skin ageing(18) |
Alpha-2-HS-Glycoprotein | With strong anti-oxidant and anti-inflammatory properties(19) |
Keratin Type I and II | For hair growth and skin regeneration(20) |
Fibulin | Delaying age-related aortic ischemia(21) |
Tetranectin | For regulation of hair color and also add moisturizing factors to the skin and hair(22) |
Talin-1 | Required for maintaining skin and hair follicle integrity.(23) |
Cartilage oligomeric matrix protein | Plays an important role in the collagen network architecture and elasticity of the skin |
Alpha-fetoprotein | Regulates proliferation of hair follicles and skin cells |
Xaa-Pro dipeptidase | Prevents skin sensitivity and other signs of skin ulcers. It plays an important role in collagen metabolism |
Filament-A | A sebaceous filament around hair follicles is required for cosmetic applications |
Apolipoprotein | Required to reduce skin inflammation, hair discoloration, and hair loss. |
Hepatocyte growth factor-like protein | Helpful in treating hair loss. |
Alpha-2 Antiplasmin | Regulates the development of dermal fibroblasts |
Phospholipid transfer proteins | Important proteins involved in lipid metabolism |
Insulin-like growth factor-binding protein 3 | Important for the regulation of the hair cycle |
CD109 antigen | Helps in the modulation of extracellular matrix synthesis in skin |
Hornerin | Helps in the normal synthesis of hair follicles. |
Cadherin 11 | A skin-improving substance regulates protein fibrosis |
Fibrinogen beta chain | Required for epidermal and hair follicle morphogenesis |
Cathepsin D | Well known for its repairing role in the photodamaged skin barrier. |
ICOS ligand | Known for improved vascularization through increased angiogenesis, essential for early wound healing |
Complement component C8 beta chain | Promotes unique wound healing ability, reduces inflammation |
Coactosin like protein | Protein very important for hair health and glowing skin |
Collagen alpha 2 (VI) chain | Important for skin and hair health |
Trangelin 2 | Supports faster wound healing |
Fibromodulin | Responsible for reduction in scar formation in the adult world. |
Contactin-1 | Supports wound healing |
Ras-related protein-rap-1b | Responsible for regulation of metabolic processes in case of inflammatory diseases like alopecia areata |
Myosin-10 | Responsible for the regulation of hair follicle proliferation, and regulation of pigmentation through the production of melanocytes during wound closure. |
Insulin-like growth factor binding protein 5 | Promotes hair growth |
Our bio activating solution is packed with several essential elements that help nourish the skin and hair, namely
- Essential Amino Acids
- Vitamins
- Humectants
- Inorganic Salts
- Coenzymes
- Stabilizers
Properties of Exosomes
Anti-Inflammatory
Exosomes carry specific "instructions" that tell your skin to dial down inflammatory molecules like TNF-α, IL-1β, and MMPs. At the same time, they encourage the production of calming agents like IL-4, IL-10, and TIMPs. The result? Reduced inflammation and a more youthful appearance.
Anti-Oxidant
Free radicals speed up the aging process and are always fighting with our skin. Do not worry, though! The exosomes from Advancexo save the day by getting rid of these free radicals with antioxidants with proteins like peroxiredoxins. It lowers oxidative stress on cells, which helps your patients look younger.
Anti-Apoptotic
Advancexo's exosomes carry anti-apoptotic messengers, nature's built-in defense against cellular aging. They work to defy the hands of time, and potentially reverse the aging process at the cellular level. The result? Healthier, longer-living skin cells contribute to a visibly younger and more radiant appearance.
Anti-Fibrotic
Advancexo's exosomes deliver a potent infusion of growth factors. These tiny messengers act like architects, stimulating the production of collagen and elastin, the building blocks of youthful skin. They promote an extracellular matrix synthesis with a healthy ratio of collagen types I and III, which promotes elasticity, smooths wrinkles, and evens texture and tone.
Immunomodulatory
Advancexo's exosomes regulate key immune cells like macrophages and T cells. They help the immune system to focus on the real threats while promoting the production of anti-inflammatory cytokines. It helps create a balanced immune response, preventing the damage caused by chronic inflammation and contributing to a more radiant appearance.
Pro-Angiogenic
Advancexo's exosomes act like tiny conductors, stimulating blood vessel growth (vascularization) by promoting endothelial cell function. This improved blood flow nourishes your skin with vital nutrients, promoting a healthy radiance.
Pro-Synthetic
Exosomes are a powerhouse of rejuvenation with several factors that can help invigorate skin cells to enhance the production of the extracellular matrix, the framework that supports collagen and elastin. This translates to firmer, plumper skin with a visibly youthful appearance.
Epigenetics
Exosomes contain specific proteins that act as keys to turn on previously inactive genes in your skin and hair cells. This process, called epigenetic modulation, allows your skin and hair scalp to express their full potential which accelerates repair, and regeneration, leading to a youthful appearance.
Advancexo Advantages
Advancexo harnesses the power of cutting-edge exosome technology to offer a safe, effective, and innovative approach to skin and hair care for your patients. Here’s what sets Advancexo apart:
- Advanced Anti-aging Barrier: Powered by cell-free bioactivated molecules, Advancexo promotes anti-inflammation and maintains the skin and scalp barrier’s integrity. This dual action helps combat visible signs of skin aging and healthy scalp to promote a healthy, youthful appearance.
- Safe and Effective Alternative: Our unique formulation leverages 300 naturally occurring, skin- and hair-essential peptides that are dermatologically tested. It delivers targeted benefits without the use of synthetic substitutes, like steroids and paraben. It makes Advancexo the prime choice for dermatologists to offer supreme skin and hair health.
- Targeted and Versatile: Advancexo offers targeted delivery, focusing its action on specific concerns like wrinkles, pigmentation, uneven texture, hair thinning, scalp problems, acne management, oil control, or hair growth. This targeted approach makes it a versatile option for diverse skin and hair types.
- Enhanced Treatment Experience: Advancexo complements more invasive treatments like laser treatment, chemical peel, or botox injection by significantly reducing post-treatment redness, burning sensations, and healing time by up to 50-60%. This translates to a more comfortable treatment experience for patients.
- Long-Shelf Life: Advancexo boasts a longer shelf life when stored at room temperature, further enhancing its user-friendliness.
Read More
Multiple Solutions, Easy Application
Exosome therapy has shown improvements in patients with
- Face wrinkles and fine lines
- Uneven skin tone or age spots
- Acne and acne scars
- Enhanced wound healing even with sensitive skin
- Loss of skin firmness
- Post-procedural redness and inflammation
- Skin texture improvement
- Hair loss due to aging
- Hair loss with a receding hairline
- Male/Female pattern baldness
- Scalp irritation
- Itchy scalp
Step 1: With the help of a syringe, draw 2-5 ml of bioactivating solution from Rejuve kit vial B.
Step 2: Transfer the drawn bioactivating solution to Rejuve kit vial A containing lyophilized exosomes.
Step 3: Gently invert the reconstituted exosomes for 30 seconds to mix the components thoroughly.
Step 4: Advancexo is ready to be mixed with any routine cosmetic applications.
Step 5: Cleanse skin thoroughly and dry it completely before application.
Step 6: Apply Advancexo reconstituted on the dried skin.
Superior Properties, Stunning Results
Exosomes
- Secreted from Stem cells
- Surplus amount of growth factors
- Reduces inflammation
- Precise control over exosome application
- Simple reconstitution process
- Easy application
- Long shelf life in lyophilized state
Vs
PRP
- Drawn from Patient’s blood
- Limited number of growth factors
- Little to no anti-inflammatory properties
- Variations in platelet application
- Requires processing time
- Tedious application procedure
- Short shelf life
Advancexo Exosomes Trusted By
Delivering Perfection in Every Vial
References
(17)Collagen Supplements for Aging and Wrinkles:A Paradigm Shift in the Fields of Dermatology
(18)Role of periostin in skin wound healing and pathologic scarformation
(14)The role of thrombospondins in wound healing, ischemia,and the foreign body reaction
FAQs
- Skin Rejuve Kit: 5 billion exosomes per vial
- Hair Rejuve Kit: 10 billion exosomes per vial