Bald patches can indicate alopecia areata, a hair loss condition that is commonly seen in children and young adults. It significantly impacts appearance, declining the self-esteem of children who are focused on their physical image at this age. The drugs fail to address the multiple aspects of this disorder.
Exosome therapy has entered the cosmetic market with its cutting-edge regenerative potential. One of its key advantages is its multitude of biological properties that can act on diversified cellular processes. It brings the change from the deep cellular level, resulting in hair restoration. This blog highlights the details of the disorder and exosome therapy for alopecia areata.
Alopecia Areata
Alopecia areata—the appearance of bald patches on the scalp. It can occur in any part of the body. There is no single causative factor that can result in the disorder. However, genetic traits, environmental factors, stress, medications, infections, etc., can result in alopecia areata.
The mechanism behind the disease is the aberrant immune response that pushes hair follicles out of the growth phase of the follicle cycle. It often leads to the shortening of hair strands with subsequent shedding and bald patches. The hallmark of the disorder is the exclamation hairs—strands that narrow in diameter as they near the scalp region. Since white strands remain unaffected, the disorder can give a false appearance of graying scalp.
Diagnosis of Alopecia Areata
Clinical diagnosis requires medical history and physical tests. Redness with bald patches suggests alopecia areata. However, a conclusive diagnosis requires dermoscopy, hair pull tests, and skin biopsy. Nails may also reveal findings in support of the disorder, such as white spots, pinpoint dents, roughness, easily split nails, etc.
The disorder can follow either of the following results:
- Since the follicle is not permanently damaged, hair can regrow on its own.
- The bald patches can expand to cause full hair loss on the scalp.
- Complete hair loss on the body, including eyebrows, hands, legs, etc.
Exosome Treatment for Hair Restoration
Exosomes—the tiny cellular parcels—carry a cargo of molecules. Enhancing cell-cell communication, exosomes contribute to complex interplay between cells. The root cause of alopecia areata is the abnormal immune pathway and the subsequent withdrawal of follicles from the hair cycle anagen phase. Exosomes for alopecia areata work on both aspects of the disorder.
Altered Immune Response
Alleviate Inflammation: Exosomes enhance the production of anti-inflammatory mediators and suppress the generation of pro-inflammatory cytokines that substantially reduce inflammation—the driving process behind alopecia areata.
Regulate Immune System: Our body has regulatory T cells, which are responsible for preventing autoimmune disorders. Exosomes elevate the levels of these cells to halt the progression of alopecia areata.
Modulate Immune Response: Exosomes incline the immune system towards healing by polarizing the macrophages from M1 to repairing M2 macrophages.
Hair Cycle Extension
Regulate Cycle: Exosomes prolong the anagen phase of the cycle responsible for follicle growth. It increases the length of strands and drives new growth while preventing excessive shedding.
Initiate New Cycle: New cycles require follicle stem cells. Exosomes directly activate the dormant stem cells. They also indirectly cause the migration of stem cell-activating cells. It leads to increased stem cell proliferation and subsequent increase in their number for more follicle cycles.
These are the ways by which exosomes exert their effects to reduce bald patches and drive new growth. However, the benefits of exosomes extend beyond these actions. Exosomes are not a problem-specific treatment, but they treat the entire scalp and improve its health in a holistic manner. The following are those additional benefits:
Hair Follicle Regeneration: Exosomes suppress the cell death pathways and prolong their survival along with proliferation.
Thicker Hair: The diameter of the bulb region in the follicle root is responsible for hair thickness. The small diameter results in thin strands. Exosomes stimulate cell proliferation in that region, thereby widening the bulb diameter and thickening the strands.
Scalp Nourishment: Blood vessels supply nutrients and oxygen to maintain scalp health. Exosomes augment the vessel quantity, thus nurturing the scalp.
Antioxidant: Reactive oxygen species (ROS) are the daily by-products of cellular processes. Although cellular proteins counter them, the levels of ROS can increase and cause significant damage to the cells. Exosomes consume them and avoid further damage to follicle cells.
Are Exosomes Safe?
Due to their novelty, exosomes are often surrounded by many misconceptions. The safety and effectiveness of the therapy are questioned from time to time. Exosomes are a scientific solution that didn’t appear in the market just on hearsay. Clinical studies have shown that exosome treatment for hair loss results in a considerable increase in the hair density on the scalp.
The improvements are substantial enough to notice. A decrease in the size of bald patches, reduced shedding, and new hair growth are observed after the treatment. All of the studies have demonstrated an absence of adverse reactions due to exosome therapy. However, precautions should be taken by using exosomes from a reliable provider and undergoing exosome therapy from a licensed dermatologist, possibly someone with prior experience in exosome therapy.
Procedure for Exosome Therapy
Exosome therapy is a simple procedure that does not require any hassle. The following procedure can inform you what to expect when you opt for the therapy.
Step 1: The consultation with the dermatologist is the first obvious step towards the therapy. The clinician evaluates the medical condition properly and confirms the underlying cause. They also determine your suitability for the therapy.
Step 2: The clinician cleans the scalp region to be treated and applies a numbing cream or anesthetic topically on the region.
Step 3: They prepare the exosome solution and infuse it into the scalp via a fine needle.
Step 4: The procedure ends with the infusion; however, the clinician might suggest some post-treatment regimens, which can enhance results.
Step 5: The exosome therapy requires multiple sessions. For best results, follow up through all the sessions and track the progress of new growth, reduced shedding, or reduced size of bald patches.
Wrapping It Up
Alopecia areata impacts the emotional health of an individual. Although medications acting on the inflammation are available, they don’t promote hair growth, mandating the administration of a different drug. Exosome therapy for hair thinning single-handedly works on inflammation and hair growth. It acts in a multidimensional manner to improve scalp health and not just treat the issue. This minimally invasive option offers visible improvements, employing its regenerative potential for hair restoration.
Advancexo has crafted unique exosomes for alopecia areata in Hair Rejuve kit after extensive scientific research and testing to bring only the best product for you.
FAQ's
It is a hair loss condition caused by an autoimmune disorder where immune cells push the hair follicles in front of the growth phase of the follicle cycle, causing bald patches.
It controls the immune system through anti-inflammatory and immune-modulatory properties and extends the growth phase of the hair cycle.
The sessions depend on the severity of the hair loss but generally range from 4-6 monthly sessions.
Exosomes are non-replicating and do not have DNA, mitigating several risks. Several scientific studies have shown that the therapy does not cause any adverse complications and is potentially safe.
