Exosome Therapy's Regenerative Effects on Skin and Hair Rejuvenation

Exosome Therapy’s Regenerative Effects on Skin and Hair Rejuvenation

Skin and Hair Rejuvenation

Exosome therapy is the latest buzzword in the field of aesthetic dermatology. It has the potential to combat hair loss and improve skin health. But why is everyone talking about it? You can think of exosomes as tiny delivery partners who are delivering a package filled with genetic material, growth factors, protein, lipids, and peptides. These factors then activate the body’s natural healing process and assist you in giving a younger appearance to your clients.

This blog will help you provide a glimpse into what exosomes are, how exosomes work, and what benefits they can provide your clients.

What are exosomes?

Every cell communicates with each other to function properly and efficiently. To do this, cells use several methods, and one such method is the use of extracellular vesicles. Among these secreted vesicles are exosomes. Exosomes are usually 30 to 150 nanometers in size and secreted by all the cells in the body. You might find it interesting that these cells are also secreted in plant cells. They do not carry the same information that human derived exosomes do. Human exosomes carry essential growth factors, peptides, lipids, and microRNAs (miRNAs) that are crucial to relaying intercellular communications.

How are exosomes extracted?

Exosome extraction begins by choosing the right source. For regenerative aesthetic medicine, exosomes are typically harvested from adult stem cells. There are two types of stem cells, predominantly used for exosome extraction. The first choice is Wharton’s jelly mesenchymal stem cells (WJ-MSCs), derived from the human umbilical cord. They carry several properties that make them a promising candidate for regenerative skin and hair care. The second choice is adipose-derived mesenchymal stem cells (ASCs), derived from fat cells.

Both of these stem cells are relatively easy to obtain from adult bodies. After the collection process, they undergo strict testing for biosafety. Once they are found to be safe for use, they are expanded in sterile conditions to ensure that these stem cells secrete exosomes with active ingredients. These secreted exosomes then undergo a rigorous purification process, making them ready for therapeutic use.

How do exosomes work?

Exosomes are brimming with several growth factors, 400 lipids, 600 miRNAs, and 300 different peptides that are enclosed in the bilipid layer. They are all set to aid in the repair and rejuvenation of damaged tissues. They are instrumental in promoting skin and hair health, particularly in anti-aging treatments. Exosomes help stimulate the production of collagen and elastin, key proteins responsible for maintaining youthful appearance. The mechanics of how exosomes function include:


  • Easy Uptake by the Target Cells: Both the exosomes and target cells are enclosed in a bilipid layer, making it easier for exosomes to deliver the active ingredients for regeneration to target cells. All the exosome has to do is fuse with the target cell’s outer layer. Along with their small size, they can easily seep into the target area upon application, with minimally invasive  treatment options.
  • Carrier of Regenerative Signals: Exosomes act as information carriers, like peptides, for crucial intercellular dialogue. When isolated from stem cells, they carry regenerative signals to stimulate repair mechanisms and promote tissue regeneration.
  • Stimulating Regeneration: The material within exosomes can activate various cellular processes. They also help reduce redness and inflammation to promote tissue regeneration.

When one applies exosomes to the target area, all the above-mentioned events start rolling and increase the natural efficiency of cellular repair and rejuvenation. Because there are no cells used, it is a cell free option. It delivers the effect of stem cells without using stem cells, making it easy to pass all the ethical considerations


Exosome Therapy in Skin Care

Exosome therapy offers a novel approach to skin care by harnessing the power of cellular communication. When applied to the skin, exosomes easily merge with skin cells and deliver the payload they are carrying. They release a cascade of growth factors and proteins into the skin cells, which initiates cellular rejuvenation.

Note: Advancexo exosomes are isolated from WJ-MSCs, which carry the same rejuvenating abilities as a developing fetus.

Once the payload is delivered, it stimulates the skin cells to produce more collagen and elastin, which are essential for maintaining the skin’s suppleness. They also help to reduce the visible signs of aging, like fine lines and wrinkles. They provide a boost to the natural cell renewal process, aiding in the repair of damaged skin. Exosomes also help promote a balanced production of melanin, leading to an even-toned complex.

Overall, exosome therapy offers a multifaceted approach to addressing the root causes of various skin concerns. It helps reduce the signs of aging and leaves your client with healthier, younger looking skin.

Benefits of Exosome Therapy in Skin Care

There are several benefits that your clients can expect after exosome treatment. Here we will share 10 benefits you can offer your clients:

Benefits of Exosome Therapy in Skin Care

  1. Reduced fine line lines and wrinkles
  2. Improved elasticity
  3. Enhanced hydration and moisture
  4. Increased firmness and suppleness
  5. Reduced pigmentation
  6. Minimizes open pores for a refined skin texture
  7. Reduction in redness and inflammation
  8. Enhanced resilience against environmental stressors
  9. Reduction of signs of fatigue
  10. Brighten dull skin with a radiant complextion.

Exosome Therapy in Hair Care

Exosome therapy offers a promising new frontier in hair care as well. Similar to skin, exosomes can readily penetrate the scalp, delivering their cargo directly to the hair follicles. This ensures the growth factors and bioactive molecules reach the hair follicles where they are most needed. Because they are loaded with a healthy dosage of bioactive molecules, they revitalize dormant hair follicles and promote new hair growth.

A healthy scalp is essential for optimal hair growth. Exosomes possess anti-inflammatory properties that can help reduce scalp irritation and inflammation. This creates a healthy environment for hair follicles to thrive and minimizes conditions that can contribute to hair loss. They also promote cell proliferation and blood vessel formation, which is crucial for nourishing hair follicles. It leads to a significant increase in hair density and combats hair loss.

Exosomes provide a holistic approach that revitalizes hair follicles, stimulates growth, and leaves your clients with healthy, luscious hair.

Benefits of Exosome Therapy in Hair Care

Similar to skin care, exosomes have a wide range of applicability in hair care as well. We will share 10 benefits that exosome treatment can provide to your clients:

Benefits of Exosome Therapy in Hair Care

  1. Stimulate hair growth by activating hair follicles.
  2. Thicker and stronger strands of hair
  3. Reduction in hair loss
  4. Improvement of Scalp Health
  5. Increased shine and luster
  6. Redction in split ends appearance
  7. Address common hair baldness
  8. Reduces scalp scarring
  9. Promotes hair follicle longevity
  10. Reduced hair follicle miniaturization

Exosome therapy has emerged as a revolutionary force in aesthetic dermatology. By harnessing the power of cellular communication, exosomes offer a natural way to rejuvenate skin and hair. These tiny powerhouses deliver a cocktail of essential growth factors, proteins, and genetic material directly to target cells and significantly enhance your skin and hair care routine.

Here are some key takeaways to remember:

  • Exosomes are a safe and minimally invasive approach to addressing various aesthetic concerns.
  • They target the root causes of skin aging and hair loss, promoting long-term results.
  • By harnessing the body’s natural regenerative abilities, exosomes offer a holistic and biocompatible solution.

If you’re looking for cutting-edge treatments to help your clients achieve their aesthetic goals, exosome therapy is definitely worth considering. It’s an exciting time to be in the field of aesthetics, and exosomes are poised to play a major role in shaping the future of beauty.


Exosomes are increadibly adaptable, and they can easily complement several aesthetic procedures, including laser therapy, chemical peels, and botox injections. Their secret lies in how they facilitate cellular communication and regeneration to significantly boost the healing process and improve efficacy.

Ideal candidates for exosome therapy are those who are struggling with early aging signs like fine lines, wrinkles, reduced skin elasticity, hair thinning, or baldness. As exosomes deliver a healthy dose of growth factors, they can stimulate skin and hair rejuvenation.

Scientists and dermatologists have put the Advancexo exosome through extensive testing to determine its safety and effectiveness. It has been deemed safe and effective for application on any skin type because it relies on the natural biological repair mechanism. In rare cases, you might see allergic reactions, but the risk can be minimized with a pre-treatment assessment