Microneedling With Exosomes

All You Need to Know About Microneedling With Exosomes

Microneedling has emerged as the preferred method for achieving youthful skin and taking care of hair fall. What if there existed a method to unlock another level of transformative outcomes? Enter microneedling with exosomes, a breakthrough making waves in the beauty industry. This groundbreaking technique merges the established advantages of microneedling with the potential of exosomes forming a combination to help you reach your desired results. If you are intrigued by this state-of-the-art procedure, look no further than this blog. We will explore all aspects of microneedling with exosomes from its mechanisms, to who stands to gain the most from it.

How does Microneedling Function?

Before delving into the realm of microneedling with exosomes, let’s dive deeper into the science behind why microneedling. Microneedling is a simple non-surgical procedure that taps into our body’s regenerative abilities. It commences with a series of needles that delicately create injuries, in the skin. Rest assured, these micro injuries are minuscule. They serve as a catalyst prompting your body’s natural healing mechanisms to spring into action. This response triggers an increase in collagen and elastin production – elements for skin. Collagen imparts firmness and structure while elastin maintains suppleness and elasticity.

Imagine microneedling as a nudge for your skin motivating it to generate more of what it requires to appear its best. The outcome? Noticeable enhancements, in skin texture, diminished lines and wrinkles and an overall youthful and radiant visage. Microneedling can even be utilized on the scalp to encourage hair growth.

There exist two instruments employed for microneedling – derma rollers and microneedle pens. Both are tools commonly utilized for scalp therapies. With sessions you can attain that sought after ” skin” glow and showcase vibrant, beautiful hair.

What is Microneedling with Exosomes?


After briefly brushing up on microneedling, let’s look at exosomes and how they can contribute a boost to the skin and hair rejuvenation process. Exosomes are tiny mailmen that deliver messages from one cell to another. They are loaded with several crucial proteins, lipids, and nucleic acids that help to regenerate and repair damaged cells. You can read about exosomes in detail here [link to exosome research blog].

When a dermatologist applies exosomes to your skin or scalp, what they do is offload their content to the target cell. Because microneedling has created small craters all over the skin and scalp, exosomes can easily enter the target area. Additionally, exosomes penetrate deep into the skin because there are tiny craters dug all over the target area. As a result, the exosomes are able to more effectively deliver their benefits and stimulate repair processes.

So, what benefits do exosomes deliver? Exosomes have a lot of components that act at the molecular level to promote skin and hair regeneration, reduce inflammation, and increase collagen production. Because the effects are implemented at the lowest level of the target cells, they can provide longer lasting results compared to other skincare and haircare products. Exosomes are not a superficial treatment but rather a cellular rejuvenation that can provide deep nourishment and repair that goes beyond just surface-level improvement.

You can think of exosomes as supercharged food for the skin and hair cells to show noticeable improvements in the health and appearance of the skin and hair, rather than just temporary fixes. They are like heroes that we bring in to help wake up the inactive skin cells and jumpstart the natural healing and renewal processes.

Several Indian dermatologists are turning to a made-in-India product, “Advancexo,” that gives a healthy dose of exosomes to the patient. But that is not all, Advancexo exosomes come loaded with coenzymes, peptides, amino acids, and growth factors that act as the building blocks for your skin’s and hair’s needs. In other words, Advancexo is a one-stop-shop for dermatologists to ensure that their clients get a healthy dose of skin and hair treatment.

What Conditions Can Exosome Microneedling Treat?

There have been positive results in treating several skin and hair conditions, including:
  • Acne scarring
  • Wrinkles
  • Fine lines
  • Hyperpigmentation
  • Melasma
  • Uneven skin tone and texture
  • Burn mark
  • Sun damage and sun spots
  • Hair loss
  • Male pattern baldness
  • Receding hairline
  • Male and female androgenetic alopecia

Exosome Microneedling Procedure

Once you decide to undergo microneedling, your dermatologist will guide you through the process. They usually ensure that you are well informed. They will apply numbing cream to the treatment area. The numbing cream is used to ensure that you won’t experience any discomfort during the procedure. Your dermatologist will let the numbing cream sit on your skin for a while before starting the treatment, usually waiting around 30 to 45 minutes for it to take effect. Afterward, they will use a dermaroller or dermapen that is appropriate for the treatment. They will start by gently puncturing the skin in the target area, making small craters in the skin. Once the target region is sufficiently punctured, they will apply an exosome product, like Advancexo, to the target area. They will ask you to keep the exosome on your face, depending on your condition. If you are interested to know, dermatologists can suggest keeping the exosome product on your face for a minimum of four hours to a maximum of 12 hours.

Microneedling with Exosomes vs. Vampire Facial

You may be thinking about trying out microneedling with exosomes or the known “vampire facial ” which is also referred to as Platelet Rich Plasma (PRP) therapy. Both treatments involve microneedling to create channels in the skin. They vary in the substances used to improve outcomes. Here’s a head-to-head comparison between the two to assist you in making a decision:
Feature Microneedling with Exosomes Vampire Facial (PRP)
Source of Growth Factors Exosomes, derived from stem cells Patient’s own Platelet-Rich Plasma (PRP)
Growth Factor Potency Potentially 100x more concentrated than PRP Moderate concentration
Preparation No blood draw is required, a pre-made exosome solution is used Blood draw and processing needed to separate PRP
Potential Benefits May offer a wider range due to exosomes’ complex cargo of molecules (collagen, proteins, etc.) Focuses on stimulating collagen and elastin production
Risk of Reaction Lower to minimal risk, as exosomes are not derived from the patient’s own blood Potential allergic reaction to patient’s own PRP
Treatment frequency Often times require 1 or 2 treatments Require up to 3 to 6 treatments to achieve results.
Recovery Time Minimal downtime. Redness and inflammation may occur but subside in 24 hours May experience slight redness and swelling for a few days
Availability A newer technology, with greater response More widely available, but is being preferred less due to drawing blood and the emergence of exosomes

Does Microneedling Hurt?

In the microneedling procedure, we tend to puncture the skin with several tiny needles. There is some expected pain for the complete procedure. So, to ensure that an individual does not feel any pain, the dermatologists apply a numbing cream over the treatment area. The sensation is often described as a prickling or scratching feeling. Your doctor will discuss your pain tolerance and adjust the numbing cream accordingly. But after seeing the microneedling with exosomes before and after, many individuals do make sure they regularly get the treatment to keep stunning, just like in their youth.

Is Microneedling with Exosomes Right for You?

Exosomes can be used with microneedling if you are looking to:
  • Improve skin tone and texture
  • Minimize scar appearance
  • Reduce hair thinning
  • Tackle signs of aging
However, discussing with your dermatologist the possibility of using exosomes in your treatment is paramount. They will carefully look into your specific needs and skin type to ensure that you receive the best treatment for skin and hair rejuvenation. It’s important to note that microneedling with exosomes may not be suitable for everyone. Before considering this treatment, it’s crucial to discuss the following cases with a dermatologist;
  • Active Skin Conditions: If you have eczema, psoriasis or other ongoing skin issues, this treatment could potentially exacerbate them.
  • Breastfeeding: For mothers caring for newborns it’s advisable to postpone microneedling treatment. The process triggers a wound healing response that could divert nutrients away from the developing fetus and potentially transfer responses through breast milk.
  • Blood Clotting Disorders: Individuals with bleeding disorders should be cautious, as microneedling can heighten the risk of bleeding from minor injuries.
  • Medical History: Certain medical conditions or medications may deem you unsuitable for microneedling with exosomes. For example, individuals prone to keloid scars may find their condition worsening with this treatment.


Microneedling with exosomes presents an interesting method for rejuvenating skin and enhancing its glow. By blending the advantages of microneedling with the potency of exosomes, this treatment provides an array of benefits for managing different skin issues. It makes microneedling with exosomes stand out as a captivating progression in the field of dermascience.


Exosome microneedling oftentimes will require you to go for 1 or 2 treatments before giving satisfactory results.

If you just undergo microneedling, it might take up to 2 months before you completely heal. However, exosomes with microneedling will reduce this specific time to a week, where the individual can return to their daily life the same day after treatment.

Microneedling with exosomes provides a promising approach to achieving smoother, younger-looking skin. It helps to:

  • Boosts collagen and elastin for younger-looking skin
  • Improves texture and evens skin tone
  • Hydrate the skin
  • addresses a wider range of concerns
  • Offer minimal to no downtime

The results of the treatment usually last from 4 months to up to a year in certain cases.