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Microneedling Enhanced with Exosomes: A Breakthrough in Skincare

“Beauty does not matter”- a phrase that has lost its footing in today’s fast-paced world. Besides the way others perceive you, appearance also shapes a person’s self-image, influencing self-esteem and confidence. But maintaining the glow on your face is not an easy task,  thanks to the pollution, dust, age and sun exposure that damage the skin’s health. 

Microneedling is an effective collagen-boosting treatment that can improve skin texture. Moreover, exosome therapy has also established a niche for itself in the rapidly changing field of skincare therapies. Its many benefits for skin issues have increased its demand in the market. Skin microneedling with Exosomes work together as a powerful combo that is raising the bar for skin care procedures. Let’s find out how exosomes boost microneedling results.

Microneedling: The Collagen Induction Treatment

Microneedling is based on the creation of microchannels or pores in the skin in a controlled manner. These channels prompt the production of collagen and elastin in the skin, thus giving it the name of collagen induction therapy. The minimal invasiveness of the procedure and the subcutaneous penetration into the skin has propelled its use in the cosmetic field. It has found applications in the treatment of wrinkles, dark spots, acne scars, stretch marks, etc.

However, these effects can be significantly amplified by pairing it up with exosome therapy.

Exosome Therapy: Redefining Skincare

Our body cells release microscopic vesicles, referred to as exosomes. They are 30-150 nm in size, almost 100-1000 times smaller than a hair strand. These vesicles are packed with various molecules such as RNAs, proteins, cytokines, growth factors, peptides, and lipids. These molecules are a part of the cellular machinery and, therefore, can regulate its processes. 

When exosomes enter a cell, they release these molecules. They orchestrate the biochemical pathways of cells to shift in the direction of recovery and healing. For example, exosomal molecules inhibit the process of degradation of collagen, elastin, and hyaluronic acid while also increasing the process of multiplication of the cells that synthesize these components. Many such modifications in cell pathways result in firmer, smoother, and hydrated skin.

The Properties of Exosomes

The potential of exosomes relies heavily on its parent cell that is synthesising and packing these vesicles. Human cells qualify as optimal cell sources since they form exosomes that can interact with human cells. Among human cells, mesenchymal stem cells (MSCs) are the best options as they encapsulate their regenerative potential along with several other features into their exosomes. The following properties of MSC-exosomes revitalize the skin:

  • Anti-apoptotic: Prevent cell death
  • Cell Regeneration: Trigger the multiplication of cells
  • Antioxidant: Consume reactive oxygen species that damage cells
  • Anti-inflammatory: Shift the immune response from cell damaging to cell repairing process.
  • Angiogenic: Increase blood vessels and the supply of nutrients and oxygen to cells.

The cells release the exosomes as a complete package laden with the required biomolecules for the repair and recovery process. So why not use this package that nature is itself producing. These packages or exosomes can be easily applied topically due to their ability to effortlessly permeate into the skin barrier. Let’s see how exosomes boost microneedling results.

Exosome Microneedling: A Powerful Combo

Exosome therapy has a lot of benefits in store that substantially strengthen the microneedling effects. Let’s have a look at the exosome microneedling benefits.

  • Enhanced Effects: Microneedling only improves the skin barrier, whereas exosomes also trigger cellular regeneration and prevent cell death.
  • Minimal Downtime: Microneedling has shorter recovery times. But the procedure is often associated with redness, dryness, itching, and flakiness. Exosome therapy, with its anti-inflammatory characteristics, can soothe these process-related adverse effects.
  • Faster Recovery: Exosomes also induce cells’ inherent healing mechanisms, minimizing the downtime of the treatment.
  • Preventive Action: Exosomes prevent further damage to skin cells by alleviating reactive oxygen species and modifying inflammatory response, thus complementing the actions of microneedling.

Step in for Microneedling with Exosomes for Skin Rejuvenation

Here is a brief procedure of microneedling with exosome treatment.

  • Consultation: A dermatologist assesses your skin to find the underlying issue and to evaluate if you are fit for the treatment.
  • Pre-Treatment: Before starting the treatment, the face is properly cleansed and a numbing cream is topically applied on the face in order to minimize the discomfort due to microneedling.
  • Microneedling: Microneedling requires a device- dermapen. Dermapen is a small handheld device that resembles a pen. The device is positioned perpendicularly on the face and stamped on the skin to create channels.
  • Exosome Therapy: The solution of exosomes is spread evenly on the face or the treated region. The channels created by microneedling enable 100% delivery of exosomes into the skin.
  • Post-Treatment Care: Microneedling results in redness on the face. Therefore, there is need of post microneedling care for face which is recommend by dermatologists. They provides some instructions for skin care for the next few days, like using mild face wash, avoiding sun exposure, etc. Follow them carefully to achieve maximum benefits.
  • Follow-up: The therapy requires more than one session to notice their full effects on the skin. So, follow up to assess the progress of each session.

What are the experts saying?

Scientists have conducted clinical studies to evaluate the potential of the combination treatment. The results have shown more improvements with the conjunction of microneedling and exosomes than employing microneedling alone. The following are the exosome microneedling benefits:

  • Improvement in skin elasticity
  • Increased skin hydration
  • Alleviation of melanin pigment
  • Enhanced blood vessel quantity
  • Reduction in wrinkles and open pores
  • More even skin tone
  • Diminished redness

Now the question arises-is microneedling with exosomes for skin rejuvenation safe? The use of combination therapy has not reported any side effects. Some temporary redness can occur due to the microneedling procedure, which exosome therapy heals. However, not following proper sterile conditions during the procedure can cause infections. Therefore, prefer an experienced and verified dermatologist for the treatment and purchase the exosomes from a reliable source.

The Right Exosomes Matter 

Many exosome solutions are available in the market and selecting one of them can be overwhelming. Following are some key points that can aid in the selection process. 

  • Among exosomes based on plant cells and human cells, human-based exosomes carry the molecules that act specifically on human cells.
  • For the regenerative effects, human stem cell-derived exosomes are the appropriate choice.
  • The exosome manufacturer should have a certified lab for preparing exosomes and should follow the proper manufacturing process.
  • The exosomes should have undergone extensive testing and characterization to ensure a quality product.
  • The product should be free from harsh chemicals or additives.

Advancexo has ticked all the above-mentioned checkboxes and formulated a special Skin Rejuve kit to avail you the next-generation exosome therapy. They have an ISO-certified BSL-2 lab and a GMP certificate, evidence of their commitment to quality and consistency. The team of Advancexo has performed rigorous testing of the product to ensure you get the best quality.

Final Thoughts

Exosome therapy is an all-rounder technology with its effects spanning varied skin problems. Microneedling is a routinely used skincare treatment. This blog explains how exosomes boost microneedling results. The effectiveness of this dynamic duo and the absence of adverse effects have promoted their use in the cosmetic field. But take caution in regards to the dermatologist and the exosome product. Advancexo has built credibility in the market owing to its adherence to quality standards. It manufactures and delivers its Skin Rejuve kit in India to present you with the future of skincare. So, opt for microneedling with exosomes for skin rejuvenation.

FAQs

Microneedling induces skin barrier restoration by collagen and elastin synthesis. Exosomes complement the microneedling by preventing further cell damage, reducing inflammation, and resulting in faster recovery.

Microneedling with exosomes has no adverse effects. Exosomes can even heal the microneedling-based redness faster.

Select a verified dermatologist to avail the treatment since the procedures performed in a non-sterile manner coils lead to infections. Also purchase the exosomes from the right manufacturer to ensure high-quality, contamination-free product.

Advancexo is an exosome manufacturer in India. The company has an ISO-certified lab for exosome preparation and a GMP certificate issued by government authorities that has built credibility in the market. The team of Advancexo runs robust tests on exosomes to present a contamination-free and pure product with high quality.

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